CENTRE NEWS
Papers accepted
Worthington, J.J., Kelemntowicz, J.E. and Travis M.A. (2010). TGF-beta: a sleeping giant awoken by integrins.Trends in Biochemical Sciences, in press.
Melton, A.C., Bailey-Bucktrout, S.L., Travis, M.A., Fife, B.T., Bluestone, J.A. and Sheppard, D. (2010). alpha(v)beta8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. Journal of Clinical Investigation, in press.
Papers published
Clark, S.J., Bishop, P.N. and Day, A.J. (2010) Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology. Biochem. Soc. Trans. 38, 1342-1348.
Public engagement

Ceri Harrop, together with Alexa Jeanes from The Manchester Museum and Steve Richardson from MHS, hosted 40 A-level students in The Hard Cell:considerations for stem cell treatments. This interactive discussion and debate activity focuses on the pros and cons of stem cell research and encourages students to develop an informed opinion on the future of stem cell therapy following their experience of the day.
Invited Talks
Clair Baldock
Extracellular Matrix as a Structural Mediator of Morphological and Homeostatic Information, Fondation des Treilles, France, 4th-9th October.
Strucutral studies on the grrrowth factor regulators - fibrillinmicrofibrils and tolloids
Andreas Prokop
Platform presentation, Cold Spring Harbor Conference on Axon Guidance, Synaptic Plasticity and Regeneration, 22nd-25th September.
Deciphering the role of spectraplakins as key orchestrators of cytoskeletal dynamics in axonal growth.
Andreas Prokop
Developmental Research Seminar Series, Sloan Kettering Institute, New York, 21st September
Spectraplakins: gigantic cytoskeletal linker molecules as key players in neuronal development
Mark Travis
European Mucosal Immunology Group Congress, Amsterdam, 29th September-2nd October.
A critical role for integrin-mediated TGF-beta activation by CD103+ dendritic cells in regulation of gut immune responses
New Staff
Sheona Drummond, Postdoc, Day/Milner lab.
Sheona worked most recently as a postdoc with John McCarthy (at MIB) focusing on the relationship between the protein translation pathway and mRNA decay. She did her PhD in Cell Biology in Dundee (‘95-‘99) on Nuclear membrane assembly in the Xenopus cell-free system.
Heather Davies, PhD student, Thornton lab.
How structure determines function of mucin glycoproteins
Poster presentations
Joanna Klementowicz
The 14th International Congress of Immunology 2010 in Kobe, Japan
αvβ8 integrin-mediated TGF-β activation by dendritic cells is required for the development of chronic gastrointestinal parasite infection
Joanna got a special travel award for this congress from British Society of Immunology.
André Koper and Andreas Prokop
Cold Spring Harbor Conference on Axon Guidance, Synaptic Plasticity and Regeneration, 22nd-25th September.
Ultrastructure and regulation of adhesion at a genetically tractable model synapse.
Aleksandr Mironov and Ling Zhang
17th International Microscopy Congress - IMC17, Rio de Janeiro, Brazil, September 19-24, 2010.
Easy modification of standard Baltec HPM 010 holders for high pressure freezing correlative light/electron microscopy.