Clark, S.J., Perveen, R., Hakobyan, S., Morgan, B.P., Sim, R.B., Bishop, P.N. & Day A.J. (2010). Impaired binding of age-related macular degeneration-associated complement factor H 402H allotype to Bruch’s membrane in human retina. J. Biol. Chem. 285, 30192-30202.
Wolny, P.M., Banerji, S., Gounon, C., Brisson, A.R., Day, A.J., Jackson, D.G. & Richter, R.P.(2010) Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronan. J. Biol. Chem. 285, 30170-30180.
Tan, K.T., Baildam, A.D., Juma, A., Day, A.J., Milner, C.M. & Bayat, A. Hyaluronan. (2011). TSG-6 and inter-αλπηα-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 experssion in contracted capsules. Aesthetic Surgery Journal (in press).
Ciani, B, Bjelic, S, Honnappa, S, Jawhari, H, Jaussi, R, Payapilly, A, Jowitt, T, Steinmetz, MO and Kammerer, RA(2010) Molecular insights into coiled-coil oligomerization state specificity. Proc Natl Acad Sci USA (in press.).
It is fantastic when some of the work within the Centre receives media attention, and we are delighted that work from Tony Day's lab was released to the press last week. The title of the press release is "Scientists discover new cause of blindness". See uom/about
Mark Travis Co-applicant on BBSRC Diet and Health Research and Industry Club (DRINC) grant with Prof. Fiona Powrie (University of Oxford) and Prof. Glenn Gibson (University of Reading). Dendritic cell subsets in the maintanence of gut health and response to bioactives. 2010-2013
Cay Kielty MRC-BHF Strategic Award with Canfield, Amaya, Whetton, Merry, Neyses £742,000. Cell-matrix biology of the mesenchymal progenitor cell niche.
Poster presentations at international conferences
The 14th International Congress of Immunology 2010 in Kobe, Japan. αvβ8 integrin-mediated TGF-β activation by dendritic cells is required for the development of chronic gastrointestinal parasite infection. Joanna received a special travel award for this congress from British Society of Immunology.
Cross talk between human lung fibroblasts and human bronchial epithelial cells regulates mucin production in vitro
Invited seminars and conference talks
The Centre held its first international conference on ECM and cell adhesion, organised by PhD students for PhD students and postdocs, earlier in the month. So, a massive congratulations and thanks to Chloe Yeung, Doug Dyer, Louise Kung and Luke Bonser for making the conference such a success. There was overwhelming positive feedback on the meeting, reflecting their hard work and dedication to organising a great meeting.
Clair Baldock The structure of collagen VI microfibrils and the role of metal‐ions in their conformation and assembly
Peter Bell The secretion of mutant V194D matrillin‐3 is unaffected by the knock‐out of matrillin‐1 in a mouse model of multiple epiphyseal dysplasia
Pat Caswell Integrin trafficking controls a RhoGTPase signalling switch to promote extension of pseudopods as cells migrate in 3D
Julia Cheung The role of beta1 integrin in mammary gland ductal morphogenesis
Fiona Foster Focal Adhesion Kinase in Breast Cancer Initiation
Sumaira Hasnain Mucins are critical components during the rejection of the enteric nematode ‘Trichuris muris’
Jon Humphries Proteomic analysis of the dynamics of integrin adhesion receptor signalling
Susan Taylor Col4a1 missense mutation reveals a role for a novel epithelium in preventing tendon adhesions
Ceri Harrop gave an enthusiastic presentation on public engagement work organised by the centre and showed the delegates a taster of how you could make your research easier to relay to the public.
Faculty Research Symposium
It is brilliant that research from the Centre was amongst the best in the Faculty this year. Not only were 4 of the 9 postgrad + postdoc talks from the Centre, but we also won both of the prizes. Congratulations to Richard Berry for winning the best postgraduate talk and to Natalia Sanchez-Soriano for winning the best postdoc talk. Also, congratulations to Joe Robertson for winning the 1st prize of the Lay Writing Competition.