Worth, D.C., Hodivala-Dilke, K., Robinson, S.D., Morton, P.E., Gertler, F.B., Humphries, M.J. and Parsons, M. (2010). αVβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and cell migration. J. Cell Biol. (in press)
Goldyn, A.M., Kaiser, P., Spatz, J.P., Ballestrem, C., and Kemkemer, R. The kinetics of force-induced cell reorganization depend on microtubules and actin. Cytoskeleton. (in press)
Wellcome to the Matrix
Next week is National Science and Engineering Week, and to celebrate this, to highlight the brilliant research that is happening in the Centre, and to raise the aspirations of school students from Greater Manchester, we are running Wellcome to the Matrix from 15th to 19th March. Many thanks to all of you who are giving up your time to get involved in what promises to be a great event. If you find yourself with 10 minutes to spare next week, please pop down to the coffee bar between 10 am and 1 pm each day and have a short chat to the students and mentors about the projects they are working on and see what the event is all about.
Served on the International Scientific Advisory Board for the University of Edinburgh MRC Centre for Regenerative Medicine (8-10 March).
Has been successful in obtaining VIP funding for 4 months to extend her work on an interdisciplinary collaboration between Prof. Brian Derby and C.Ballestrem studying how vinculin activity influences the mechanical properties of cells using the acoustic microscope and the atomic force microscope.
On 28th November 2009, the 1st Centre Lentiviral meeting was held. Around 20 people from 11 groups in the Centre took part in an open discussion on establishing co-operative approaches to lentiviral technology. Pengbo Wang (Streuli lab) gave a talk on using lentiviral shRNA in mammary epithelial cells. The feedback on this meeting was excellent and it was agreed to hold these meetings every 3 months. The 2nd Centre Lentiviral meeting took place on 11th February with Colette Inkson and Gareth Hyde (both Canfield Lab) giving talks on applying the lentiviral system to over-expressing proteins in cells (Lenti viral mediated gene overexpression in primary vascular cells: the problems and progress so far). The next meeting will be take place in May.
Friday 12th March, Integrative and Systems Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, ER stress as a pathogenic factor in cartilage
Wednesday 3rd March, University of Leeds, Unzipping coiled-coil olgomerization
Friday 5th March, Paul Scherrer Institut, Villingn, Switzerland, Recombinat protein production: from basic research to service contract
Tuesday 9th March, spoke at annual meeting of the SFBMEc (French Society of Extracellular Matrix Biology). Vinculin activity controls the adhesion machinery.
(A. Carisey, R. Tsang, A. Nazgiewicz and C. Ballestrem)