Centre News

News

2013
- 17 May
- 19 April
- 22 March
- 22 February
- 8 February
- 18 January
2012
- 20 December
- 23 November
- 9 November
- 12 October
- 28 September
- 10 August
- 6 July
- 1 June
- 21 May
- 27 April
- 13 April
- 23 March
- 9 March
- 24 February
- 10 February
- 27 January
2011
- 16 December
- 2 December
- 18 November
- 21 October
- 23 September
- 9 September
- 29 July
- 15 July
- 23 June
- 10 June
- 20 May
- 6 May
- 15 April
- 1 April
- 18 March
- 4 March
- 18 February
- 4 February
- 21 January
2010
- 17 December
- 26 November
- 12 November
- 22 October
- 8 October
- 24 September
- 10 September
- 20 August
- 6 August
- 23 July
- 25 June
- 11 June
- 28 May
- 14 May
- 29 April
- 16 April
- 1 April
- 12 March
- 26 February
- 12 February
- 29 January
- 15 January

Papers published

Beecher, N., Roseman, A.M., Jowitt, T.A., Berry, R., Troilo, H., Kammerer, R.A., Shuttleworth, C.A., Kielty, C.M., Baldock, C. (2011). Collagen VI: Conformation of A-domain arrays and microfibril architecture. J Biol Chem. Epub PubMed.

Papers accepted

Kalson, N., Holmes, D., Lu, Y., Herchenhan, A., Starborg, T., Kadler, K. (2011). Slow stretching that mimics embryonic growth rate stimulates structural and mechanical development of tendon-like tissue in vitro. Developmental Dynamics in press.

Suleman, F., Gualeni, B., Gregson, H.J., Leighton, M.P., Piróg, K.A., Edwards, S., Holden, P., Boot-Handford R.P., Briggs, M.D.(2011). A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia. Human Mutationin press.

Invited talks and conferences

Mike Briggs

Cutting Edge lecture series in Translational paediatrics, Royal Manchester Children’s Hospital, 8 September.

Skeletal Dysplasias: The Long and the Short of their Biology and Treatment

Tony Day

RSC Carbohydrate Group Meeting "Carbohydrates: Key Interactors at the Chemistry-Biology Interface", Liverpool, 15-16 September.

Hyaluronan/protein complexes: different forms and functions of a giant polysaccharide

Doug Dyer

24^th UK Adhesion Metting, Birmingham, 22 September.

TSG-6 binds to CXCL8 and modulates its activity

Congratulations to Doug for winning a prize for the best talk at the meeting

Natalia Sánchez-Soriano

22nd European Drosophila Research Conference, Lisbon, Portugal, 21-24 September.

Understanding microtubule regulation during nervous system development

XIV Congreso Nacional de la Sociedad Española de Neurociencia", Salamanca, Spain,

Spectraplakins - cytoskeletal integrators with key roles in neuronal growth

Mark Travis

25th Annual European Macrophage and Dendritic Cell Society Meeting, Brussels, 22-24 September.

Intestinal dendritic cells are specialised to activate TGF-beta and induce Foxp3+ Tregs via integrin alphav beta8

BSMB Autumn meeting, Matrix Signals – Cell-Matrix Interactions in Health and Disease, Newcastle University, Newcastle, 8-9 September.

Talks

Plenary talk Christoph Ballestrem Vinculin a mechanotransducer regulates the recruitment and release of FA proteins

Peter Bell The trafficking of mutant matrillin-3 is not affected by the deletion of matrillin-1 in a mouse model of multiple epiphyseal dysplasia (EMD5 type)

Luke Bonser Evidence for conformational changes in the polymeric mucin MUC5AC following release from the secretory granule

Doug Dyer TSG-6 binds to CXCL8 and modulates its activity

Susan Taylor A role for collagen IV in preventing tendon adhesions

Posters

Simon Foulcer The G1 domain of human versican binds to hyaluronan co-operatively, reversing pericellular matrix formation in a model system

Louise Kung Investigating the role of endoplasmic reticulum stress in chondrodysplasias

Chloé Yeung Discovery of Arhgap28, a putative GTPase activating protein expressed during tendon development

Congratulations to Chloé for winning the poster prize

Poster presentations

Barbara Schellenberg

“Mitochondrial Dynamics: from mechanism to disease” Sardinia, Italy, 11-15 September.

Does Mcl-1 regulate apoptosis commitment in epithelial cells?

Other news

Clair Baldock has been awarded Chair of Diamond Light Source peer review panel 2 (Soft Condensed matter) until November 2013.

Congratulations to Ray Boot-Handford who has taken up the role of Associate Dean for Postgraduate Research.

Ilaria Laface from Instituto Clinico Humanitas, Milan, Italy, visited the Cell-Matrix Centre on 21 September; Ilaria is a joint PhD student (registered through The Open University) between Dr. Barbara Bottazzi (Milan) and Tony Day, and the purpose of her visit was to discuss her first year progress (Title of project: Migration Stimulating Factor (MSF): a novel marker for tumor progression).

Welcome to the following new PhD students:

Rebecca Brading (Brennan lab) Investigating Edar signalling in Tumourigenesis

Rebecca Bridgewater (Caswell lab) Integrin endocytic trafficking in differentiation and development of cancer

Tom Denny (Lennon lab) The renal glomerulus as a model of extracellular matrix production in differentiation and normal ageing

Tom Fenton (Travis lab) The role of integrins, TGF-beta and dendritic cells in controlling intestinal tolerance in humans

Chloe Lallyett (Kadler lab) Identification and commercialisation of microcurrent induced genes

Lorna Mullan (Briggs/Boothandford lab) Genetic approaches to assessing the role of ER stress pathways in the pathogenesis of chondrodysplasias

Mike Randles (Lennon lab) Proteomic analyses of kidney glomerular extracellular matrix in health and disease

Samantha Roberts (Kielty lab) Notch signalling in mesenchymal stem cells

De-Yeo (Adam) Wang (Ballestrem lab) The role of mechanical and chemical signals in adhesion signalling of neurons

Public engagement

Following on from Ceri's "Taking Matrix Public" presentation at Tuesday's First Year Symposium, if anyone fancies getting involved in any aspect of the Centre's public engagement work, or perhaps you have ideas of your own, or maybe you'd just like to find out a bit more about what is involved, please contact Ceri at ceri.harrop@manchester.ac.uk or in Smith D3401.