Beecher, N., Roseman, A.M., Jowitt, T.A., Berry, R., Troilo, H., Kammerer, R.A., Shuttleworth, C.A., Kielty, C.M., Baldock, C. (2011). Collagen VI: Conformation of A-domain arrays and microfibril architecture. J Biol Chem. Epub PubMed.
Kalson, N., Holmes, D., Lu, Y., Herchenhan, A., Starborg, T., Kadler, K. (2011). Slow stretching that mimics embryonic growth rate stimulates structural and mechanical development of tendon-like tissue in vitro. Developmental Dynamics in press.
Suleman, F., Gualeni, B., Gregson, H.J., Leighton, M.P., Piróg, K.A., Edwards, S., Holden, P., Boot-Handford R.P., Briggs, M.D.(2011). A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia. Human Mutationin press.
Invited talks and conferences
Cutting Edge lecture series in Translational paediatrics, Royal Manchester Children’s Hospital, 8 September.
Skeletal Dysplasias: The Long and the Short of their Biology and Treatment
RSC Carbohydrate Group Meeting "Carbohydrates: Key Interactors at the Chemistry-Biology Interface", Liverpool, 15-16 September.
Hyaluronan/protein complexes: different forms and functions of a giant polysaccharide
24th UK Adhesion Metting, Birmingham, 22 September.
TSG-6 binds to CXCL8 and modulates its activity
Congratulations to Doug for winning a prize for the best talk at the meeting
22nd European Drosophila Research Conference, Lisbon, Portugal, 21-24 September.
Understanding microtubule regulation during nervous system development
XIV Congreso Nacional de la Sociedad Española de Neurociencia", Salamanca, Spain,
Spectraplakins - cytoskeletal integrators with key roles in neuronal growth
25th Annual European Macrophage and Dendritic Cell Society Meeting, Brussels, 22-24 September.
Intestinal dendritic cells are specialised to activate TGF-beta and induce Foxp3+ Tregs via integrin alphav beta8
BSMB Autumn meeting, Matrix Signals – Cell-Matrix Interactions in Health and Disease, Newcastle University, Newcastle, 8-9 September.
Plenary talk Christoph Ballestrem Vinculin a mechanotransducer regulates the recruitment and release of FA proteins
Peter Bell The trafficking of mutant matrillin-3 is not affected by the deletion of matrillin-1 in a mouse model of multiple epiphyseal dysplasia (EMD5 type)
Luke Bonser Evidence for conformational changes in the polymeric mucin MUC5AC following release from the secretory granule
Doug Dyer TSG-6 binds to CXCL8 and modulates its activity
Susan Taylor A role for collagen IV in preventing tendon adhesions
Simon Foulcer The G1 domain of human versican binds to hyaluronan co-operatively, reversing pericellular matrix formation in a model system
Louise Kung Investigating the role of endoplasmic reticulum stress in chondrodysplasias
Chloé Yeung Discovery of Arhgap28, a putative GTPase activating protein expressed during tendon development
Congratulations to Chloé for winning the poster prize
“Mitochondrial Dynamics: from mechanism to disease” Sardinia, Italy, 11-15 September.
Does Mcl-1 regulate apoptosis commitment in epithelial cells?
Clair Baldock has been awarded Chair of Diamond Light Source peer review panel 2 (Soft Condensed matter) until November 2013.
Congratulations to Ray Boot-Handford who has taken up the role of Associate Dean for Postgraduate Research.
Ilaria Laface from Instituto Clinico Humanitas, Milan, Italy, visited the Cell-Matrix Centre on 21 September; Ilaria is a joint PhD student (registered through The Open University) between Dr. Barbara Bottazzi (Milan) and Tony Day, and the purpose of her visit was to discuss her first year progress (Title of project: Migration Stimulating Factor (MSF): a novel marker for tumor progression).
Welcome to the following new PhD students:
Rebecca Brading (Brennan lab) Investigating Edar signalling in Tumourigenesis
Rebecca Bridgewater (Caswell lab) Integrin endocytic trafficking in differentiation and development of cancer
Tom Denny (Lennon lab) The renal glomerulus as a model of extracellular matrix production in differentiation and normal ageing
Tom Fenton (Travis lab) The role of integrins, TGF-beta and dendritic cells in controlling intestinal tolerance in humans
Chloe Lallyett (Kadler lab) Identification and commercialisation of microcurrent induced genes
Lorna Mullan (Briggs/Boothandford lab) Genetic approaches to assessing the role of ER stress pathways in the pathogenesis of chondrodysplasias
Mike Randles (Lennon lab) Proteomic analyses of kidney glomerular extracellular matrix in health and disease
Samantha Roberts (Kielty lab) Notch signalling in mesenchymal stem cells
De-Yeo (Adam) Wang (Ballestrem lab) The role of mechanical and chemical signals in adhesion signalling of neurons
Following on from Ceri's "Taking Matrix Public" presentation at Tuesday's First Year Symposium, if anyone fancies getting involved in any aspect of the Centre's public engagement work, or perhaps you have ideas of your own, or maybe you'd just like to find out a bit more about what is involved, please contact Ceri at firstname.lastname@example.org or in Smith D3401.