Centre News

News

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Press release

New work from the Humphries lab (paper below) has been highlighted by the Wellcome Trust: wellcome.ac.uk

Papers published

Bass MD, Williamson RC, Nunan RD, Humphries JD, Byron A, Morgan MR, Martin P, Humphries MJ. (2011). A Syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis. Developmental Cell. Epub PubMed.

Canty-Laird EG, Lu Y, Kadler KE. (2011). Step-wise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ. Biochem J. Epub PubMed.

Papers accepted

Dozynkiewicz, M.A., Jamieson, N.B., MacPherson, I., Grindlay, J., van den Berghe, P., von Thun, A., Morton, J.P., Gourley, C., Timpson, P., Nixon, C., McKay, C.J., Carter, R., Strachan, Anderson, K., Sansom, O.J., Caswell*, P.T. and Norman*, J.C. (2011). Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Developmental Cell In press. *Joint corresponding authors

Invited talks

Keith Brennan

The Notch meeting, Athens, Greece, 2-7 October, Crosstalk between Wnt and Notch signalling pathways in vertebrates

Mark Travis

Max F. Perutz Laboraties, Vienna, Austria, 20 October, Keeping immunity in check: the role of integrins, TGF-beta and dendritic cells in controlling immune responses

Keynote speaker, Medical University of Vienna and Max F Perutz Laboratories Joint Post-doc retreat on Inflammation and Infection on Friday 21st October in Golls, Austria.

Poster presentation

Ana HIdalgo Sastre

The Notch meeting, Athens, Greece, 2-7 October, Notch, two ways to limit Wnt

Public engagement

Science Spectacular

Please help out if you can on Saturday 29 October, from 11 am-3 pm, at the Whitworth Hall and The Manchester Museum.

In conjunction with colleagues from across FLS and the University, we are hosting 'Science Spectacular' as part of this year's Manchester Science Festival celebrations at the Whitworth Hall and Manchester Museum.

The Cell-Matrix Centre has several stands, including lung, eye, flies and heart. If you are interesting in being part of a team to help out for a couple of hours on the day please get in touch with Ceri at ceri.harrop@manchester.ac.uk or in D3401.

Pop along with your friends, families and children to explore the gut, make slime, trick your brain, explore the wonderful world of flies, actually see the back of your own eye and explore how the heart works.

Please see details at: sciencespectacular

We'd like to welcome new staff to the Cell-Matrix Centre

Sundas Chohan has joined the Kadler lab as a PhD student to work on Understanding the molecular basis of tissue tension

Sarah Farrar is a new PhD student who has joined a joint project in the Kielty and Canfield labs to work on Cell-matrix biology of the mesenchymal progenitor cell niche

Amanda Gallagher has joined the Thornton lab as a postdoc. She will be working on Protection against intestinal helminth infection: Role of the novel intestinal mucin MUC5AC with Dave and Richard Grencis.

Yue Qu has joined the Prokop lab as a PhD student to work on Mechanistic links between signalling pathways and cytoskeletal regulation

International Scientific Advisory Board

This week saw a visit by our international scientific advisors. These are all high profile scientists working in the cell-matrix research area, and were here to see presentations by PIs, our core facilities and public engagement, and posters presented by postdocs and postgrads. They were all very impressed by the work going on here, and will be advising us on our future scientific strategy and goals. A big thank you to everyone who was involved with the visit and discussing their work with the ISAB members. The ISAB team was:

Chris Chen, Skirkanich Professor of Innovation, University of Pennsylvania, Philadelphia

David Critchley, Professor of Biochemistry, University of Leicester, Leicester

Rick Horwitz, Professor of Cell Biology, University of Virginia, Charlottesville

Clare Isacke, Professor of Molecular Cell Biology, Director of the Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London

Bjorn Olsen, Hersey Professor of Cell Biology, Dean for Research, Harvard School of Dental Medicine, Boston

Congratulations to...

Simon Clark and Sally Williamson (ex-Thornton lab) who had their baby, Benjamin on 1 October. Benjamin was 7lb and 15oz and both mother baby are doing well.

Other news

Karl Kadler was invited to Sanofi-aventis (Chilly-Mazarin, Paris) as a member of their advisory panel on fibrosis research.