New work from the Humphries lab (paper below) has been highlighted by the Wellcome Trust: wellcome.ac.uk
Bass MD, Williamson RC, Nunan RD, Humphries JD, Byron A, Morgan MR, Martin P, Humphries MJ. (2011). A Syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis. Developmental Cell. Epub PubMed.
Canty-Laird EG, Lu Y, Kadler KE. (2011). Step-wise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ. Biochem J. Epub PubMed.
Dozynkiewicz, M.A., Jamieson, N.B., MacPherson, I., Grindlay, J., van den Berghe, P., von Thun, A., Morton, J.P., Gourley, C., Timpson, P., Nixon, C., McKay, C.J., Carter, R., Strachan, Anderson, K., Sansom, O.J., Caswell*, P.T. and Norman*, J.C. (2011). Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Developmental Cell In press. *Joint corresponding authors
The Notch meeting, Athens, Greece, 2-7 October, Crosstalk between Wnt and Notch signalling pathways in vertebrates
Max F. Perutz Laboraties, Vienna, Austria, 20 October, Keeping immunity in check: the role of integrins, TGF-beta and dendritic cells in controlling immune responses
Keynote speaker, Medical University of Vienna and Max F Perutz Laboratories Joint Post-doc retreat on Inflammation and Infection on Friday 21st October in Golls, Austria.
We'd like to welcome new staff to the Cell-Matrix Centre
Sundas Chohan has joined the Kadler lab as a PhD student to work on Understanding the molecular basis of tissue tension
Sarah Farrar is a new PhD student who has joined a joint project in the Kielty and Canfield labs to work on Cell-matrix biology of the mesenchymal progenitor cell niche
Amanda Gallagher has joined the Thornton lab as a postdoc. She will be working on Protection against intestinal helminth infection: Role of the novel intestinal mucin MUC5AC with Dave and Richard Grencis.
Yue Qu has joined the Prokop lab as a PhD student to work on Mechanistic links between signalling pathways and cytoskeletal regulation
International Scientific Advisory Board
This week saw a visit by our international scientific advisors. These are all high profile scientists working in the cell-matrix research area, and were here to see presentations by PIs, our core facilities and public engagement, and posters presented by postdocs and postgrads. They were all very impressed by the work going on here, and will be advising us on our future scientific strategy and goals. A big thank you to everyone who was involved with the visit and discussing their work with the ISAB members. The ISAB team was:
Chris Chen, Skirkanich Professor of Innovation, University of Pennsylvania, Philadelphia
David Critchley, Professor of Biochemistry, University of Leicester, Leicester
Rick Horwitz, Professor of Cell Biology, University of Virginia, Charlottesville
Clare Isacke, Professor of Molecular Cell Biology, Director of the Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London
Bjorn Olsen, Hersey Professor of Cell Biology, Dean for Research, Harvard School of Dental Medicine, Boston
Simon Clark and Sally Williamson (ex-Thornton lab) who had their baby, Benjamin on 1 October. Benjamin was 7lb and 15oz and both mother baby are doing well.
Karl Kadler was invited to Sanofi-aventis (Chilly-Mazarin, Paris) as a member of their advisory panel on fibrosis research.