CENTRE NEWS
Papers published
Arozarena, I., Bischof, H., Gilby, D., Belloni, B, Dummer, R. and Wellbrock, C. (2011) In melanoma, beta-catenin acts as a suppressor of invasion through a cell-type specific mechanism. Oncogene. In press.
Byron, A., Humphries, J.D., Bass, M.D., Knight, D. and Humphries, M.J. (2011) Proteomic analysis of integrin adhesion complexes. Sci. Signal. 4: pt2
Mahoney, D.J., Swales, C., Athanasou, N.A., Bombardieri, M., Pitzalis, C., Kliskey, K., Sharif, M., Day, A.J., Milner, C.M. & Sabokbar, A. (2011) TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with OPG. Arthritis Rheum. 63, 1034-1043.
Grants awarded
Dave Thornton (with Richard Grencis, FLS)Wellcome Trust project grant, Protection against intestinal helminth infection: Role of the novel intestinal mucin MUC5AC
Invited talks
Clair Baldock
Institut de Biologie et Chimie des Protéines,CNRS, Lyon, 6 April. Structure, assembly and function of tolloid proteinases and elastic fibre molecules
Pat Caswell
Birmingham UK endocytosis conference, 4-5 April. Integrin trafficking controls RhoGTPase signalling to promote invasive migration
Martin Humphries
School of Biosciences, University of Cardiff, 6 April. Insights from mass spectrometric analyses of adhesion signalling
Karl Kadler
British Society for Matrix Biology, Bristol, 11 April. Understanding how tendon precursor cells tension the extracellular matrix
Department of Bioengineering, Imperial College London, March 16. Understanding how cell-generated forces shape tissue
Institute of Molecular, Cellular and Systems Biology, School of Life Sciences, University of Glasgow, 5 April. Understanding how cell-generated forces shape tissue morphology
Andreas Prokop Spectraplakins - cytoskeletal integrators with key roles in brain development
Centro de Biología Molecular Severo, Ochoa (CBM), Madrid, Spain,11 April.
Instituto de Biomedicina de Valencia,(IBV-CSIC), Valencia, Spain, 12 April.
Instituto de Biología Molecular de Barcelona (IBMB), Spain; Cell and Developmental Biology series, 13 April.
Universidad Pompeu Fabra (UPV)/ Centro de Regulación Genómica (CRG), Barcelona, Spain; 14 April.
Mark Travis
BBSRC Diet and Research Industry Club (DRINC) Dissemination event, Bristol, 14 April. Dendritic Cell Subsets in Maintanence of Gut Health and Response to Bioactives.
Conferences
‘Injury and Repair Mechanisms in Chronic Airway Disease', London, 7-8 April:
Luke Bonser
Poster: Incomplete mucin maturation may contribute to the pathology of chronic airway disease
Ceri Harrop
Talk: Cell-cell cross-talk in vitro regulates mucin production
Simon Clark and Tony Day's work on AMD was talked about by Paul Bishop at the 30th Annual Meeting of British Association for Ophthalmic Pathology (BAOP), Manchester. 7-8 April. Age-related macular degeneration and the Y402H polymorphism in complement factor H.
Public engagement
Ceri Harrop and Stephen Richardson delivered 'A Hard Cell: Considerations into Stem Cell Therapy' on Wed 6th April for 25 A-Level Students from Stockport College. The event was held at the Manchester Museum and organised by Alexa Jeanes.
Other news
Following publication of the Tropoelastin paper in PNAS Clair Baldock was invited to submit an article for the Diamond Light Source Annual Report 2011 on our work. The article is entitled "Nanostructure and elastic properties of human tropoelastin" by Clair Baldock, Tim J Wess & Anthony S. Weiss.