CENTRE NEWS
Papers accepted
Byron, A., Humphries, J.D., Craig, S.E., Knight, D. and Humphries, M.J. (2012). Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment. Proteomics in press.
Paper published
Zhang, S., He, H., Day, A.J. & Tsang, S.C.G. (2012). Constitutive expression of IaI family proteins by human amniotic membrane epitherlial and stromal cells supporting formation of the HC-HA complex. J. Biol. Chem. 287, 12433-44. PubMed
Invited talks
Clair Baldock
50th Anniversary meeting of the French Society for Extracellular Matrix Biology, Paris, 29-30 March. Structural Studies on BMP Regulators
Christoph Ballestrem
Public Health Department, Harvard Medical School, Boston, USA, 20 March. Vinculin - a mechanotransducer in control of the adhesion network
Ray Boot-Handford
50th Anniversary meeting of the French Society for Extracellular Matrix Biology, Paris, 29-30 March. The pathogenic consequences of chondrocyte endoplasmic reticulum stress
Pat Caswell
Institute of Pharmacology, University of Marburg, 29 March. Integrin trafficking controls invasive migration of cancer cells
Tony Day
School of Medicine's Science Seminar Series, Cardiff University, 29 March. Hyaluronan/protein interactions in inflammation: structural & functional diversity of a giant polysaccharide
Mark Morgan
Centre for Biological Sciences, University of Southampton, 27 March. Syndecan-4: Environmental sensor and environmental regulator
Mark Travis
British Society of Immunology Infection and Immunity Affinity Group Meeting, London, 29 March. The role of integrins, dendritic cells and TGF-beta in regulating immunity to intestinal worm infection
BSMB and DGBF joint meeting , St. Catherine's College, University of Oxford, 2nd-4th of April, 2012
Tim Hardingham chaired the Stem Cells and their niche session and Ray Boot-Handford chaired the Cell Adhesion and Signalling session. And, Mike Briggs drove the Matrix on Tour bus (see below!)
Talks
Claire Hartley, ARMET and CRELD2 are secreted ER-stress related proteins that demonstrate substrate specificity in skeletal dysplasias
Louise Kung, Hypertrophic chondrocytes have a limited capacity to cope with Increases in endoplasmic reticulum stress without triggering the unfolded protein response
Posters
Rawshan Choudhury, Fibulin-4 regulates latent TGFbeta1 through heparan sulphate interactions
Sarah Edwards, Creld2 is an ER stress related protein that possesses putative PDI-like activity and shows distinct substrate specificity
Claire Hartley, ARMET and CRELD2 are secreted ER-stress related proteins that demonstrate substrate specificity in skeletal dysplasias
Lorna Mullan, Pharmacological chaperones as a potential treatment for chondrodysplasia caused by collagen X mutations
Other news
The Thornton lab has a French 2nd year undergraduate student doing a 2 month work placement at the moment – Lisa Troise from the Institut Universitaire de Technologie de l'Universite of Monpellier
Poster presentations
Amanda Gallagher, British Society of Parasitology meeting at the University of Strathclyde, 3-5 April. Protection at mucosal barriers: The effect of multiple Trichuris muris challenge infections on the expression of the mucin Muc5ac
Rebecca Taylor, BHF Symposium 2012, UCL Institute of Child Health, London, 29 March. Elucidating the role of TSG-6 in vascular calcification
New staff
Ahmet Acar is a new postdoc in the Brennan lab. Ahmet completed his PhD under the supervision of Akira Orimo at the Paterson Institute and will be working on Developing robust markers for Notch signalling in breast cancer
Diana Ruiz (Hilda Diana Alejandra Ruiz Nivia) has joined the Baldock lab as a technician. Diana was previously working in Paul Bishop's lab.
Congratulations to...
Peter Bell from the Briggs lab who successfully defended his PhD thesis, The trafficking of mutant matrillin-3 is not affected by the deletion of matrillin-1 in a mouse model of multiple epiphyseal dysplasia (EMD5 type), on 22 March. David Young (Newcastle) was the external examiner and Clair Baldock was the internal examiner.
