About us

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An interdisciplinary research centre embedded within the Faculty of Life Sciences at The University of Manchester.

For everyone

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'Get Connected’ the annual conference of the Wellcome Trust Centre for Cell-Matrix Research was held In Manchester between 10-12th September 2014. The focus of the meeting this year was the cellular microenvironment, one of the Centre’s key themes. The programme was masterfully designed and organised by Holly Brunton (PDRA in the Wellbrock lab), Ed Horton (PhD student in the Humphries Lab) and Ahmet Ucar (PDRA in the Streuli lab) and the event, attended by 80 participants, was a huge success. Read more

Our discoveries

Our core facilities

Our public engagement activities

Our research

Our publications

Latest News

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Viva success for Centre PhD students: Holly Birchenough (The Biophysical Characterisation of TSG-6: A Structural and Functional Investigation, Day lab) & Heather Davies (Investigation of the gastrointestinal mucus barrier: identification of the polymeric mucins, their structure and interacting proteins, Thornton lab) Read more

Upcoming events

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Molecular control of growth cone adhesion, clutching and invasion Read more

Latest Discoveries

 
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Fibrillin microfibrils are essential elements of dynamic connective tissues, that are often found at epithelial-mesenchymal interfaces such as the dermal-epithelial junction. Deposition of microfibrils by mesenchymal cells is fibronectin-dependent; much less is known about their deposition by epithelial cells. Read more

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Collagen is the main structural protein in connective tissues in animals and exists as ordered bundles of fibrils in tendons, ligaments, bone and skin. Collagen fibrils can be several millimeters in length, making them the longest, largest and most size-variable polymers known. Until now, the precise cellular location of their manufacture and the transport of these large proteins was not understood. Read more