About us


An interdisciplinary research centre embedded within the Faculty of Life Sciences at The University of Manchester.

Job opportunities in the Centre

Vacancy for Professorial Chair in Cell-Matrix Research
A major new cell matrix research role, working with funding from the Wellcome Trust. Read more

Independent Research Fellows Call
We offer an attractive and flexible fellowship scheme for potential fellows who are competitive for external fellowships, or independent research fellows who have substantive external funding. Read more

For everyone


The end of November saw our very first book club on 'The Immortal Life of Henrietta Lacks'.  Other book groups have shown much interest so this will run into the New Year and beyond.   Read more

Our discoveries

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Latest News


Grants awarded                                                                            Cay Kielty, MRC project grant, May 2014-June 2017. Pericellular mechanisms of fibrillin microfibril assembly               Press release                                                              Pekovic-Vaughan, V., Gibbs, J., Yoshitane, H., Yang, N., Pathiranage, D., Guo, B., Sagami, A., Taguchi, K., Bechtold, D., Loudon, A., Yamamoto, M., Chan, J., van der Horst, G.T., Fukada, Y. and Meng, Q.J. Read more

Upcoming events

Angela Nieto is Full Professor at the Instituto de Neurociencias (CSIC-UMH) in Alicante, Spain, and Head of the institute's Developmental Neurobiology Unit. Read more

Latest Discoveries


Stem cells have enormous potential to be used in the treatment of a wide variety of diseases because of their ability to convert into many different types of cell. However, this kind of “regenerative medicine”, which is sometimes called tissue engineering, requires the ability to direct their conversion into the cell type of choice. This has proved very difficult to achieve because we do not sufficiently understand what controls the conversion process or what dictates the type of cell that is Read more


Cartilage is the tissue that lines the articulating surfaces of joints, allowing smooth gliding of the joint surfaces and providing shock absorbing properties.  In osteoarthritis, the cartilage becomes damaged and joint movement is compromised and frequently painful.  Many studies have shown that osteoarthritis results from complex combinations of genetic and environmental factors. Increasing age is one of the major susceptibility factors, although how age causes increased susceptibility remains Read more